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KMID : 0385020010170040275
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Korean Journal of Laboratory Animal Science
2001 Volume.17 No. 4 p.275 ~ p.282
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Reference values of body weight, blood pressure, hematology and serum biochemistry in the Sprague-Dawley(SD) rats from 24 to 30 months
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Abstract
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A reference values comprising body weight gain, blood glucose, blood pressure, heamatology, serum biochemistry and anatomopathological study in the Sprague-Dawley (SD) rats Pram 24 to 30 months is described. Comparisons between age and sex were analysed. Weight gain, blood glucose, blood pressure, and haematology in both sexes followed patterns consistent with other studies. Light microscopic observations of fiver and kidney showed vacuolar degeneration, diffuse necrosis and fibrosis of cytoplasm, and vascular congestion, atrophy of glomerulus and fibrosis of glomerular epithelium, respectively The data provide reference values for use in toxicological and other investigation.
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KEYWORD
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